Frank Tacke was originally educated at the medical school in Hannover, Germany, and Baylor College of Medicine, Houston, TX. Later he stayed at University of Texas, M.D. Anderson Cancer Center in Houston, working on new gene therapy strategies (1998-1999) as well as for a post-doctoral research training (2004-2006) at the Mount Sinai Medical Center, New York, working on monocyte/macrophage and dendritic cell biology. Since 2006, he is a clinical physician and leader of a research laboratory at the University Hospital Aachen, Germany. He is board-certified in Internal Medicine, Gastroenterology and Critical Care Medicine. His research interests are: Clinical and Experimental Hepatology, Liver Immunology, Viral Hepatitis, Gastroenterology, Critical Care Medicine, and Monocyte/Macrophage Biology. In 2012, Frank Tacke was appointed as an Associate Professor (W2-professorship) at the RWTH University Aachen. He has (co‑)authored >180 peer-reviewed original and review articles.
For the last several years, important lines of research in Frank Tacke’s research team included the regulation of inflammatory responses in the liver, novel imaging approaches to dissect immune cell subsets in injured liver, factors driving the progression to fibrosis and cancer, targeting these cellular or molecular mechanisms by nanoparticles and the translation into clinics (biomarkers + therapy). He has been furthermore involved in several clinical trials, mainly focussed on improving therapies for acute liver failure, chronic hepatitis B, hepatitis C, liver cirrhosis and hepatocellular carcinoma.